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Female subjects
|
Male subjects
|
|---|
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Total, N
|
4665
|
4287
|
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Age (years)
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57.0 ± 12.2
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57.9 ± 12.6*
|
|
Diabetes, N (%)
|
521 (11.2)
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722 (16.8)*
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|
Smoker, N (%)
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910 (19.5)
|
965 (22.5)*
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|
Hypertension, N (%)
|
2094 (44.9)
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2350 (54.8)*
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|
Statin therapy, N (%)
|
423 (9.1)
|
707 (16.5)*
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CKD risk groups, N (%)
|
|
Low CKD risk
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3911 (83.8)
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3526 (82.2)*
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|
Moderate CKD risk
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518 (11.1)
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506 (11.8)
|
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High CKD risk
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117 (2.5)
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144 (3.4)*
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Very high CKD risk
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42 (0.9)
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53 (1.2)
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BMI (kg/m2)
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27.1 ± 5.4
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27.6 ± 4.2*
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WHR
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0.9 ± 0.1
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1.0 ± 0.1*
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|
SBP (mmHg)
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125.1 ± 17.2
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131.7 ± 15.5*
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DBP (mmHg)
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73.9 ± 9.6
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76.7 ± 9.9*
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Cystatin C (mg/l)
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0.9 ± 0.2
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1.0 ± 0.2*
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|
eGFRCys (ml/min per 1.73m2)
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86.0 ± 19.1
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86.8 ± 20.2
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Urinary albumin-creatinine ratio (mg/g)
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18.6 ± 118.6
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29.6 ± 214.4*
|
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Fasting glucose (mmol/l)
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5.5 ± 1.1
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5.9 ± 1.2*
|
|
Fasting insulin (pmol/l)
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62.6 ± 113.7
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70.6 ± 54.6*
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HbA1c (%)
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5.4 ± 0.5
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5.4 ± 0.6*
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Total cholesterol (mmol/l)
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5.7 ± 1.1
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5.4 ± 1.1*
|
|
HDL cholesterol (mmol/l)
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1.8 ± 0.5
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1.4 ± 0.4*
|
|
Non-HDL cholesterol (mmol/l)
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3.9 ± 1.1
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4.0 ± 1.1*
|
|
LDL cholesterol (mmol/l)
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3.5 ± 1.0
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3.5 ± 1.0
|
|
TG (mmol/l)
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1.2 ± 0.7
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1.6 ± 1.3*
|
|
ApoA1 (g/l)
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1.8 ± 0.3
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1.5 ± 0.2*
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ApoB (g/l)
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1.1 ± 0.3
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1.1 ± 0.3*
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|
Lp(a) (g/l)
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0.2 ± 0.3
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0.2 ± 0.3*
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hsCRP (mg/l)
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3.1 ± 6.1
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2.5 ± 4.7*
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IL-6 (ng/l)
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3.5 ± 4.7
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3.8 ± 4.9*
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ALAT (μkat/l)
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0.4 ± 0.2
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0.5 ± 0.3*
|
|
ASAT (μkat/l)
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0.4 ± 0.1
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0.5 ± 0.2*
|
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AP (μkat/l)
|
1.2 ± 0.4
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1.1 ± 0.3
|
|
GGT (μkat/l)
|
0.5 ± 0.6
|
0.8 ± 0.9*
|
- Values for mean ± standard deviation or total number (percentage) are shown. p values were assessed by the t test or chi-squared test and corrected for multiple testing based on the false discovery rate method. *p < 0.05 for female vs. male subjects
- ALAT, alanine aminotransferase; AP, alkaline phosphatase; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; ASAT, aspartate aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; eGFRCys, cystatin C-based estimated glomerular filtration rate; GGT, gamma-glutamyltransferase; HbA1c, glycated hemoglobin A1c; HDL, high-density lipoprotein; hsCRP, high-sensitivity C-reactive protein; IL, interleukin; LDL, low-density lipoprotein; Lp(a), lipoprotein(a); SBP, systolic blood pressure; TG, triglycerides; WHR, waist-to-hip ratio
