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|
No.
|
Strategy
|
Screening coverage, c (%)
|
Screening interval, t (years)
|
Active zero- detections, za
|
Total cost (<DOLLAR/>)
|
Total DALYs
|
ACER (<DOLLAR/>/DALY)
|
ICER (<DOLLAR/>/DALY)
|
|---|
|
1
|
Passive surveillance only1
|
0
|
N/A
|
N/A
|
25754 [12267, 40807]
|
2488.8 [1207.8, 3912.6]
|
Minimum cost
|
Minimum cost
|
|
2
|
Biennial screening with one zero for cessation
|
55
|
2
|
1
|
42517 [23546, 62968]
|
1338.9 [437.8,1755.7]
|
14.6
|
14.62
|
|
3
|
Biennial screening with two zeros for cessation
|
55
|
2
|
2
|
43066 [24432, 63133]
|
1339.4 [436.3,1755.5]
|
15.1
|
Dominated
|
|
4
|
Biennial screening with three zeros for cessation
|
55
|
2
|
3
|
43501 [25092, 63266]
|
1340.1 [434.8,1756.5]
|
15.4
|
Dominated
|
|
5
|
Annual screening with one zero for cessation
|
55
|
1
|
1
|
48885 [26628, 72263]
|
1027.9 [570.3, 2262.7]
|
15.8
|
20.43
|
|
6
|
Annual screening with two zeros for cessation
|
55
|
1
|
2
|
49571 [27896, 72428]
|
1027.7 [570.6, 2264.3]
|
16.3
|
2501.44
|
|
7
|
Annual screening with three zeros for cessation
|
55
|
1
|
3
|
50163 [28670, 72806]
|
1027.4 [572.9, 2261.9]
|
16.7
|
2772.35
|
- 1The comparator strategy. 2Relative to Strategy 1. 3Relative to Strategy 2. 4Relative to Strategy 5. 5Relative to Strategy 6.
- We show the mean total cost (to nearest dollar) and the total number of DALYs (to the nearest 0.1 DALYs) for each strategy with the 95% prediction intervals across all stochastic realisations. The ACER is the change in cost over the change in DALYs averted as compared to the baseline strategy, whilst the ICER is compared to the next best strategy (given in the table footnotes). Costs are denominated in 2018 US dollars
