Sensitivity and specificity of the Bamberg Dementia Screening Test’s (BDST) full and short versions: brief screening instruments for geriatric patients that are suitable for infectious environments

Table 4 Diagnostic accuracy of the BDST and the MMSE (95% confidence intervals in parentheses). SEN sensitivity, SPE specificity, AUC area under the curve, Dem_mo moderate dementia, Dem_mi mild dementia, Dem_{mi_alz} mild dementia Alzheimer’s disease, Dem_{mi_other} mild dementia, other types than Alzheimer’s disease, BDST Bamberg Dementia Screening Test, BDST_s Bamberg Dementia Screening Test, short form (sum score for the first and second subtest), BDST_us Bamberg Dementia Screening Test, ultra-short form (only score for the first subtest), MMST Mini-Mental State Examination. (1) Following the German Guideline for dementia, the MMSE scores were considered to distinguish between mild and moderate forms of dementia. Therefore, no measures of diagnostic accuracy can be presented for the MMSE and moderate dementia

		Dem_mo vs. CNT	Dem_mi vs. CNT	Dem_{mi_alz} vs. CNT	Dem_{mi_other} vs. CNT	Dem_mi or Dem_mo vs. CNT
MMSE	Cut-off	(1)	≤ 26/30	≤ 26/30	≤ 26/30	≤ 26/30
	SEN		.76 (.73–.79)	.79 (.76–.83)	.72 (.67–.76)	.81 (.79–.83)
	SPE		.88 (.82–.93)	.88 (.82–.93)	.88 (.82–.93)	.88 (.82–.93)
	NPV		.36 (.31–.41)	.52 (.46–.59)	.54 (.47–.60)	.35 (.30–.40)
	PPV		.98 (.96–.99)	.96 (.94–.98)	.94 (.91–.97)	.98 (.97–.99)
	AUC		.88 (.86–.91)	.90 (.88–.92)	.86 (.83–.88)	.91 (.89–.93)
BDST	Cut-off	≤ 31/50	≤ 37/50	≤ 37/50	≤ 37/50	≤ 37/50
	SEN	1.000	.93 (.91–.94)	.94 (.92–.96)	.91 (.88–.94)	.94 (.93–.95)
	SPE	1.000	.82 (.75–.88)	.82 (.75–.88)	.82 (.75–.88)	.82 (.75–.88)
	NPV		.63 (.56–.70)	.77 (.70–.84)	.77 (.70–.84)	.62 (.54–.69)
	PPV		.97 (.96–.98)	.95 (.93–.97)	.93 (.90–.96)	.98 (.97–.99)
	AUC	1.000	.95 (.94–.97)	.96 (.95–.97)	.94 (.92–.96)	.96 (.95–.97)
BDST_s	Cut-off	≤ 15/18	≤ 16/18	≤ 16/18	≤ 16/18	≤ 16/18
	SEN	.94 (.91–.96)	.84 (.81–.86)	.87 (.85–.90)	.79 (.75–.83)	.86 (.84–.88)
	SPE	.93 (.89–.97)	.70 (.62–.77)	.70 (.62–.77)	.70 (.62–.77)	.70 (.62–.77)
	NPV	.88 (.82–.93)	.40 (.34–.46)	.59 (.52–.67)	.55 (.48–.62)	.26 (.22–.30)
	PPV	.97 (.94–.99)	.95 (.93–.96)	.92 (.89–.94)	.87 (.84–.91)	.99 (.98–.99)
	AUC	.97 (.95–.98)	.86 (.83–.88)	.89 (.86–.91)	.81 (.78–.85)	.88 (.86–.90)
BDST_us	Cut-off	≤ 9/10	–	–	–	≤ 9/10
	SEN	.85 (.81–.89)				.58 (.55–.61)
	SPE	.86 (.81–.92)				.85 (.79–.91)
	NPV	.74 (.67–.81)				.20 (.16–.23)
	PPV	.93 (.89–.96)				.97 (.96–.98)
	AUC	.90 (.87–.93)				.73 (.70–.77)

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