Gestational lipid profile as an early marker of metabolic syndrome in later life: a population-based prospective cohort study

Table 3 Association of maternal lipid levels in early pregnancy with metabolic syndrome six years after pregnancy (n = 3510)

	Without metabolic syndrome n = 3160	With metabolic syndrome OR (95% CI) n = 350	P-value
Total cholesterol, SDS	Reference	1.30 (1.16 to 1.45)	< 0.001
Triglycerides, SDS	Reference	2.43 (2.14 to 2.75)	< 0.001
LDL-c, SDS	Reference	1.36 (1.22 to 1.51)	< 0.001
HDL-c, SDS	Reference	0.51 (0.46 to 0.58)	< 0.001
Remnant cholesterol, SDS	Reference	2.43 (2.14 to 2.76)	< 0.001
Non-HDL-c, SDS	Reference	1.66 (1.49 to 1.86)	< 0.001

Values are odds ratios (95% confidence interval) derived from multiple logistic regression analyses. Basic model: adjusted for maternal age, gestational age at blood sampling, ethnicity, educational level, parity, smoking and folic acid supplementation. Abbreviations: SDS, SD-scores; CI, confidence interval; OR, odds ratio; LDL-c, low-density lipoprotein cholesterol; HDL-c, high-density lipoprotein cholesterol

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